Direct Measurement of Torque Induced Telomere Strand Invasion using Magnetic Tweezers
نویسندگان
چکیده
منابع مشابه
Magnetic Tweezers for the Measurement of Twist and Torque
Single-molecule techniques make it possible to investigate the behavior of individual biological molecules in solution in real time. These techniques include so-called force spectroscopy approaches such as atomic force microscopy, optical tweezers, flow stretching, and magnetic tweezers. Amongst these approaches, magnetic tweezers have distinguished themselves by their ability to apply torque w...
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15 صفحه اولApplying torque to the Escherichia coli flagellar motor using magnetic tweezers
The bacterial flagellar motor of Escherichia coli is a nanoscale rotary engine essential for bacterial propulsion. Studies on the power output of single motors rely on the measurement of motor torque and rotation under external load. Here, we investigate the use of magnetic tweezers, which in principle allow the application and active control of a calibrated load torque, to study single flagell...
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INTRODUCTION: Proteoglycan (PG) aggregate is a major component of the extracellular matrix in articular cartilage, and is assumed to be responsible for resisting compression. To date, however, this important mechanical function has never been demonstrated at the molecular level. The goal of this study was to present a method for direct measurement of the compressive properties of single PG aggr...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2018
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2017.11.515